[Activate vitamin D3 or bisphosphonate in glucocorticoid-induced osteoporosis]

Abstract

Glucocorticoid therapy is associated with bone loss starting soon after the therapy is initiated and an increased risk of fracture. Activated forms of vitamin D(3), which are frequently prescribed for postmenopausal osteoporosis in Japan, are one of a useful agent to prevent glucocorticoid-induced osteoporosis. In this review, the effect of activate form vitamin D(3) is compared with plain vitamin D or bisphosphonate.