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Review
. 2007 Jan;40(1):3.e11-6.
doi: 10.1016/j.jelectrocard.2006.04.002. Epub 2006 Nov 1.

The early repolarization variant--normal or a marker of heart disease in certain subjects

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Review

The early repolarization variant--normal or a marker of heart disease in certain subjects

John P Boineau. J Electrocardiol. 2007 Jan.

Abstract

The theory is advanced that the early repolarization variant may not always be benign and that it can become a substrate for ventricular arrhythmias, sudden death, and hypercontractility cardiomyopathy in some subjects, including certain high-performance athletes. In addition, it is suggested that it likely represents part of a spectrum of cardiovascular anomalies related to nonischemic ST elevation including Brugada syndrome, and that it may also have a molecular genetic origin of variable penetrance.

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