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doi: 10.1016/j.cell.2006.10.025.
The HeArt of regeneration
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- PMID: 17081969
- DOI: 10.1016/j.cell.2006.10.025
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The HeArt of regeneration
Cell.
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Abstract
Fish and amphibian hearts are known to regenerate after partial resection, but the molecular mechanisms underlying this process remain unclear. In this issue of Cell, Lipilina et al. analyze regeneration in the zebrafish heart. Their work indicates that new cardiomyocytes originate from undifferentiated progenitor cells and reveals a critical role for the epicardium, the cellular layer that covers the heart.
Comment on
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A dynamic epicardial injury response supports progenitor cell activity during zebrafish heart regeneration.Cell. 2006 Nov 3;127(3):607-19. doi: 10.1016/j.cell.2006.08.052. Cell. 2006. PMID: 17081981
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