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. 2006 Dec;114(6):411-6.
doi: 10.1111/j.1600-0447.2006.00821.x.

The persistence of depression score

J Spijker  1 , R de Graaf, J Ormel, W A Nolen, D E Grobbee, H Burger
Affiliations

The persistence of depression score

J Spijker et al. Acta Psychiatr Scand. 2006 Dec.

Abstract

Objective: To construct a score that allows prediction of major depressive episode (MDE) persistence in individuals with MDE using determinants of persistence identified in previous research.

Method: Data were derived from 250 subjects from the general population with new MDE according to DSM-III-R. These subjects were recruited from the Netherlands Mental Health Survey and Incidence Study (NEMESIS), using the Composite International Diagnostic Interview. Determinants for persistence were transformed into a practical risk score using proportional hazards models and bootstrapping techniques.

Results: The risk of MDE persistence after 12 months was 23%. The score comprised measures of physical illness, social support, depression severity and recurrency, and duration of previous episodes. With increasing categories of these measures, the predicted risks increased from 7 to 40%.

Conclusion: We constructed the Persistence of Depression Score (PDS) showing reasonable performance. The PDS could be of importance in clinical practice to support treatment decisions.

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