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. 2007 Jan;51(1):390-3.
doi: 10.1128/AAC.00921-06. Epub 2006 Nov 6.

Mosaic staphylococcal cassette chromosome mec containing two recombinase loci and a new mec complex, B2

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Mosaic staphylococcal cassette chromosome mec containing two recombinase loci and a new mec complex, B2

R Heusser et al. Antimicrob Agents Chemother. 2007 Jan.

Abstract

A novel staphylococcal cassette chromosome (SCC) mec from a clinical methicillin-resistant Staphylococcus aureus isolate (ST100/CC5) had a mosaic structure, composed of SCC DNA from several different backgrounds. It harbored two complete ccr loci and a new variant of mec complex B, with DeltamecR1 interrupted by the aminoglycoside resistance transposon Tn4001.

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Figures

FIG. 1.
FIG. 1.
Genetic map of the mosaic SCCmec element from MRSAZH47. Open reading frames are symbolized by arrows, and the bars below them indicate homologies to previously described SCC elements. Integration site sequences for SCCmec (*), direct repeats of chromosomal junctions (◂), and inverted repeats (▹) are indicated. JL denotes the junction proximal and JR the junction distal to the origin of replication.

References

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