doi: 10.1007/BF00169045.
Effects of Bay K 8644 on the spontaneous electrical and mechanical activities of the rat portal vein
Affiliations
- PMID: 1708854
- DOI: 10.1007/BF00169045
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Effects of Bay K 8644 on the spontaneous electrical and mechanical activities of the rat portal vein
Naunyn Schmiedebergs Arch Pharmacol.
1990 Nov.
Abstract
Effects of Bay K 8644 on the spontaneous electrical and mechanical activities of the rat portal vein were studied. Bay K 8644 enhanced contractions in amplitude and duration. Bay K 8644 prolonged the duration of the spontaneous spike potential bursts and increased the number of spike potentials in a burst. These results indicate that the increase in the amplitude and duration of spontaneous contractions of the rat portal vein induced by Bay K 8644 are mediated mainly by the facilitation of the membrane electrical activity.
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