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Case Reports
. 2007 Jul;18(7):827-9.
doi: 10.1007/s00192-006-0241-4. Epub 2006 Nov 7.

Urinary hesitancy and retention during treatment with sertraline

L Lowenstein  1 , E R Mueller, S Sharma, M P FitzGerald
Affiliations
Case Reports

Urinary hesitancy and retention during treatment with sertraline

L Lowenstein et al. Int Urogynecol J Pelvic Floor Dysfunct. 2007 Jul.

Abstract

We report the cases of two women who began to experience urinary hesitancy and retention after starting treatment with sertraline for depression. Discontinuation of the drug resulted in complete symptom relief. Serotonergic neurons are involved at several levels in control of the lower urinary tract. Retention is apparently an uncommon complication of sertraline. Discontinuation should be considered for patients presenting with voiding difficulties.

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