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. 2007 Mar;86(3):199-204.
doi: 10.1007/s00277-006-0203-4. Epub 2006 Nov 7.

Genetic variation of FUT2 in a Ghanaian population: identification of four novel mutations and inference of balancing selection

Mikiko Soejima  1 , Hao Pang, Yoshiro Koda
Affiliations

Genetic variation of FUT2 in a Ghanaian population: identification of four novel mutations and inference of balancing selection

Mikiko Soejima et al. Ann Hematol. 2007 Mar.

Abstract

The FUT2 is rich in polymorphisms that show population-specific patterns in its coding sequence. In this study, we found four novel substitutions in 121 Ghanaian samples. In addition, statistical tests considering population expansion scenarios suggested that balancing selection might be responsible for the genetic diversity of FUT2 in this population.

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