Cloning and sequencing of human FSH receptor cDNA
- PMID: 1709010
- DOI: 10.1016/0006-291x(91)91682-3
Cloning and sequencing of human FSH receptor cDNA
Erratum in
- Biochem Biophys Res Commun 1994 Jun 15;201(2):1057
Abstract
We have isolated and sequenced a cDNA encoding the follicle stimulating hormone (FSH) receptor. The deduced amino acid sequence (678 residues) containing seven putative transmembrane segments which displays sequence similarity to G protein-coupled receptors. The receptor consists of 359 residue extracellular domain which contains four N-linked glycosylation sites. While the protein is 89% identical overall with the previously cloned rat FSH receptor, the most highly conserved regions are the putative transmembrane segments (95% similarity).
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