Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2007 Jan 26;25(7):1161-6.
doi: 10.1016/j.vaccine.2006.10.020. Epub 2006 Oct 25.

Occurrence of severe gastroenteritis in pups after canine parvovirus vaccine administration: a clinical and laboratory diagnostic dilemma

Nicola Decaro  1 , Costantina Desario, Gabriella Elia, Marco Campolo, Alessio Lorusso, Viviana Mari, Vito Martella, Canio Buonavoglia
Affiliations

Occurrence of severe gastroenteritis in pups after canine parvovirus vaccine administration: a clinical and laboratory diagnostic dilemma

Nicola Decaro et al. Vaccine. .

Abstract

A total of 29 faecal samples collected from dogs with diarrhoea following canine parvovirus (CPV) vaccination were tested by minor groove binder (MGB) probe assays for discrimination between CPV vaccine and field strains and by diagnostic tests for detection of other canine pathogens. Fifteen samples tested positive only for CPV field strains; however, both vaccine and field strains were detected in three samples. Eleven samples were found to contain only the vaccine strain, although eight of them tested positive for other pathogens of dogs. Only three samples were found to contain the vaccine strain without evidence of canine pathogens. The present study confirms that most cases of parvovirus-like disease occurring shortly after vaccination are related to infection with field strains of canine parvovirus type 2 (CPV-2) rather than to reversion to virulence of the modified live virus contained in the vaccine.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Carmichael L.E., Binn L.N. New enteric viruses in the dog. Adv Vet Sci Comp Med. 1981;25:1–37. - PubMed
    1. Parrish C.R., Aquadro C.F., Strassheim M.L., Evermann J.F., Sgro J.-Y., Mohammed H.O. Rapid antigenic-type replacement and DNA sequence evolution of canine parvovirus. J Virol. 1991;65:6544–6552. - PMC - PubMed
    1. Buonavoglia C., Martella V., Pratelli A., Tempesta M., Cavalli A., Buonavoglia D. Evidence for evolution of canine parvovirus type-2 in Italy. J Gen Virol. 2001;82:1555–1560. - PubMed
    1. Nakamura M., Tohya Y., Miyazawa T., Mochizuki M., Phung H.T., Nguyen N.H. A novel antigenic variant of canine parvovirus from a Vietnamese dog. Arch Virol. 2004;149:2261–2269. - PubMed
    1. Decaro N, Martella V, Desario C, Bellacicco AL, Camero M, Manna L, et al. First detection of canine parvovirus type 2c in pups with haemorrhagic enteritis in Spain. J Vet Med B Infect Dis Vet Public Health, in press. - PMC - PubMed

Publication types

MeSH terms