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Case Reports
. 2007 Jan;56(1):148-53.
doi: 10.1016/j.jaad.2006.05.068. Epub 2006 Sep 6.

Rituximab for the treatment of the skin manifestations of dermatomyositis: a report of 3 cases

Hope V Dinh  1 , Christopher McCormack, Stephen Hall, H Miles Prince
Affiliations
Case Reports

Rituximab for the treatment of the skin manifestations of dermatomyositis: a report of 3 cases

Hope V Dinh et al. J Am Acad Dermatol. 2007 Jan.

Abstract

Three patients suffering from classic dermatomyositis (juvenile and adult-onset) with prominent recalcitrant skin manifestations are described. All patients demonstrated good control of muscle symptoms on immunosuppressive medications, but their cutaneous disease persisted despite treatment with at least 4 different systemic treatments and topical agents. They were given rituximab, a monoclonal anti-CD20 antibody, achieving a response with minimal side effects. We document our experience with this medication for the cutaneous lesions of dermatomyositis.

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