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Review
. 2006 Nov;25(5):697-700.
doi: 10.1016/j.immuni.2006.10.005.

Thymus exclusivity: all the right conditions for T cells

Hiromi Iwasaki  1 , Koichi Akashi
Affiliations
Free article
Review

Thymus exclusivity: all the right conditions for T cells

Hiromi Iwasaki et al. Immunity. 2006 Nov.
Free article

Erratum in

  • Immunity. 2006 Dec;25(6):1003

Abstract

A fraction of primitive "lymphoid" precursors retain plasticity for myeloid differentiation. In this issue of Immunity, Laiosa et al. describe that Notch-Delta signals can protect thymic precursors from reprogramming into the myeloid lineage, antagonizing the enforced myeloid transcription factors such as PU.1 and C/EBPalpha.

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