Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1991 Mar;29(3):483-7.
doi: 10.1128/jcm.29.3.483-487.1991.

Antibody response to serotype-specific and cross-reactive neutralization epitopes on VP4 and VP7 after rotavirus infection or vaccination

K Taniguchi  1 , T Urasawa, N Kobayashi, M U Ahmed, N Adachi, S Chiba, S Urasawa
Affiliations

Antibody response to serotype-specific and cross-reactive neutralization epitopes on VP4 and VP7 after rotavirus infection or vaccination

K Taniguchi et al. J Clin Microbiol. 1991 Mar.

Abstract

By using a competitive solid-phase immunoassay with serotype-specific and cross-reactive neutralizing monoclonal antibodies directed at VP4 and VP7, we tested the antibody responses to some neutralization epitopes on VP4 and VP7 in individuals infected or vaccinated with rotavirus. Antibody responses to VP7 epitopes of the infecting serotype of virus were found at a high frequency in both infants and children. In contrast, antibody responses to VP4 and heterotypic VP7 were observed only when the individuals possessed antibodies to any serotype of rotavirus in their acute-phase or prevaccination sera.

PubMed Disclaimer

References

    1. Eur J Immunol. 1973 Apr;3(4):235-40 - PubMed
    1. Arch Virol. 1984;81(1-2):1-12 - PubMed
    1. J Gen Virol. 1991 Jan;72 ( Pt 1):117-24 - PubMed
    1. J Gen Virol. 1990 Nov;71 ( Pt 11):2615-23 - PubMed
    1. J Clin Microbiol. 1990 Dec;28(12):2837-41 - PubMed

Publication types

LinkOut - more resources