Review
[Histone modification and regulation of chromatin function]
[Article in
Russian]
- PMID: 17100086
Item in Clipboard
Review
[Histone modification and regulation of chromatin function]
[Article in
Russian]
Genetika.
2006 Sep.
Abstract
Nucleosomes play two main roles, acting as basal units in DNA compaction and coordinating most processes in chromosomes. The coordination is due to modification of histones, proteins forming nucleosomes. The review briefly describes the nucleosome structure and major modifications of histones and considers the role of such modifications in transcriptional suppression and activation.
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