Review
doi: 10.4161/cc.5.20.3365.
Epub 2006 Oct 16.
The mitotic spindle matrix: a fibro-membranous lamin connection
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- PMID: 17102624
- DOI: 10.4161/cc.5.20.3365
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Review
The mitotic spindle matrix: a fibro-membranous lamin connection
Cell Cycle.
2006 Oct.
Free article
Abstract
The mitotic spindle apparatus has attracted the attention of cell biologists for decades. Whereas the main function of this microtubule-based system is to segregate chromosomes, spindle morphogenesis and chromosome segregation must also coordinate with the segregation of the whole cell. The finding that RanGTPase stimulates the assembly of a lamin B-containing membranous matrix in mitosis(1) may provide a connection between the segregation of mitotic chromosomes and the partitioning of membrane systems during cell division.
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