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Review
. 2006 Oct;5(20):2345-7.
doi: 10.4161/cc.5.20.3365. Epub 2006 Oct 16.

The mitotic spindle matrix: a fibro-membranous lamin connection

Yixian Zheng  1 , Ming-Ying Tsai
Affiliations
Free article
Review

The mitotic spindle matrix: a fibro-membranous lamin connection

Yixian Zheng et al. Cell Cycle. 2006 Oct.
Free article

Abstract

The mitotic spindle apparatus has attracted the attention of cell biologists for decades. Whereas the main function of this microtubule-based system is to segregate chromosomes, spindle morphogenesis and chromosome segregation must also coordinate with the segregation of the whole cell. The finding that RanGTPase stimulates the assembly of a lamin B-containing membranous matrix in mitosis(1) may provide a connection between the segregation of mitotic chromosomes and the partitioning of membrane systems during cell division.

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