The analysis of underivatized oligosaccharides by matrix-assisted laser desorption mass spectrometry
- PMID: 1710893
- DOI: 10.1016/0006-291x(91)91837-3
The analysis of underivatized oligosaccharides by matrix-assisted laser desorption mass spectrometry
Abstract
Matrix Assisted Laser Desorption Mass Spectrometry is shown to provide a rapid and sensitive technique for the analysis of underivatized oligosaccharides. Typical sample loading is 1 pmol and analysis time is around 5 minutes. Through the use of an internal standard, mass measurements are generally accurate to within 0.5 Da. The technique is particularly useful for the analysis of oligosaccharide mixtures released from glycoproteins.
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