Current concepts and controversies in the treatment of alcoholic hepatitis
- PMID: 17109510
- PMCID: PMC4087332
- DOI: 10.3748/wjg.v12.i43.6909
Current concepts and controversies in the treatment of alcoholic hepatitis
Abstract
The treatment of alcoholic hepatitis remains one of the most debated topics in medicine and a field of continued research. In this review, we discuss the evolution of scoring systems, including the recent development of the Glasgow alcoholic hepatitis score, role of liver biopsy and current treatment interventions. Studies of treatment interventions with glucocorticoids, pentoxifylline, infliximab, s-adenosyl-methionine, and colchicine are reviewed with discussion on quality. Glucocorticoids currently remain the mainstay of treatment for severe alcoholic hepatitis.
References
-
- Alcohol-attributable deaths and years of potential life lost--United States, 2001. MMWR Morb Mortal Wkly Rep. 2004;53:866–870. - PubMed
-
- Kim WR, Brown RS Jr, Terrault NA, El-Serag H. Burden of liver disease in the United States: summary of a workshop. Hepatology. 2002;36:227–242. - PubMed
-
- Rehm J, Room R, Monteiro M, Gmel G, Graham K, Rehn N, Sempos CT, Jernigan D. Alcohol as a risk factor for global burden of disease. Eur Addict Res. 2003;9:157–164. - PubMed
-
- O'Shea RS, McCullough AJ. Treatment of alcoholic hepatitis. Clin Liver Dis. 2005;9:103–134. - PubMed
-
- Mathurin P. Corticosteroids for alcoholic hepatitis--what's next. J Hepatol. 2005;43:526–533. - PubMed
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
