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Review
. 2006 Dec;26(4):751-72.
doi: 10.1016/j.cll.2006.07.002.

Lipoprotein(a): a unique risk factor for cardiovascular disease

Erdembileg Anuurad  1 , Michael B Boffa, Marlys L Koschinsky, Lars Berglund
Affiliations
Review

Lipoprotein(a): a unique risk factor for cardiovascular disease

Erdembileg Anuurad et al. Clin Lab Med. 2006 Dec.

Abstract

Lipoprotein(a) (Lp(a)) is present in humans and primates. It has many properties in common with low-density lipoprotein, but contains a unique protein moiety designated apo(a), which is linked to apolipoprotein B-100 by a single disulfide bond. International standards for Lp(a) measurement and optimized Lp(a) assays insensitive to isoform size are not yet widely available. Lp(a) is a risk factor for coronary artery disease, and smaller size apo(a) is associated with coronary artery disease. The physiologic role of Lp(a) is unknown.

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