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Case Reports
. 1975 Jul;21(1):32-38.

Thymus transplantation. Reconstitution of cellular immunity in a four-year-old patient with T-cell deficiency

L Businco, E Rezza, G Giunchi, F Aiuti
Case Reports

Thymus transplantation. Reconstitution of cellular immunity in a four-year-old patient with T-cell deficiency

L Businco et al. Clin Exp Immunol. 1975 Jul.

Abstract

The case is reported of a 4-year-old girl affected with recurrent infections; anaemia, thrombocytopenia, haemorrhages and hepatosplenomegaly. Immunological investigations revealed a defect in cellular immunity related to the thymus-dependent system, hypergammaglobulinaemia (especially of class IgE), and very high titres of antibodies against Epstein-Barr virus (EBV). After foetal thymus transplantation, correction of the immunological defect and significant clinical improvement were noted, as well as a decrease of IgE and EBV antibody titres.

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References

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