Review
doi: 10.1016/j.ejmech.2006.09.019.
Epub 2006 Nov 15.
A review of anti-infective and anti-inflammatory chalcones
Affiliations
- PMID: 17112640
- DOI: 10.1016/j.ejmech.2006.09.019
Item in Clipboard
Review
A review of anti-infective and anti-inflammatory chalcones
Eur J Med Chem.
2007 Feb.
Abstract
Chalcones, considered as the precursors of flavonoids and isoflavonoids, are abundant in edible plants, and have also been shown to display a diverse array of pharmacological activities. The purpose of this review is to provide an overview of the pharmacological activity of synthetic and naturally occurring chalcones. This review is complementary to earlier reviews and covers more recent reports of antimicrobial activity of chalcones (antibacterial and antifungal), as well as antileishmanial, antimalarial, antiviral and anti-inflammatory activities of these compounds.
Similar articles
-
Synthesis and biological screening of a combinatorial library of beta-chlorovinyl chalcones as anticancer, anti-inflammatory and antimicrobial agents.Bioorg Med Chem. 2010 Mar 1;18(5):2060-5. doi: 10.1016/j.bmc.2009.12.077. Epub 2010 Jan 11. Bioorg Med Chem. 2010. PMID: 20138527
-
Substituted quinolinyl chalcones and quinolinyl pyrimidines as a new class of anti-infective agents.Eur J Med Chem. 2009 May;44(5):2081-91. doi: 10.1016/j.ejmech.2008.10.011. Epub 2008 Nov 1. Eur J Med Chem. 2009. PMID: 19028410
-
Synthesis and biological evaluation of a novel series of pyrazole chalcones as anti-inflammatory, antioxidant and antimicrobial agents.Bioorg Med Chem. 2009 Dec 15;17(24):8168-73. doi: 10.1016/j.bmc.2009.10.035. Epub 2009 Oct 22. Bioorg Med Chem. 2009. PMID: 19896853
-
Therapeutic Perspectives of Aminoflavonoids-A Review.Int J Mol Sci. 2025 Feb 25;26(5):2014. doi: 10.3390/ijms26052014. Int J Mol Sci. 2025. PMID: 40076638 Free PMC article. Review.
-
Anti-inflammatory trends of 1, 3-diphenyl-2-propen-1-one derivatives.Mini Rev Med Chem. 2013 Jan;13(1):87-94. Mini Rev Med Chem. 2013. PMID: 22876943 Review.
Cited by
-
Novel chalcone/aryl carboximidamide hybrids as potent anti-inflammatory via inhibition of prostaglandin E2 and inducible NO synthase activities: design, synthesis, molecular docking studies and ADMET prediction.J Enzyme Inhib Med Chem. 2021 Dec;36(1):1067-1078. doi: 10.1080/14756366.2021.1929201. J Enzyme Inhib Med Chem. 2021. PMID: 34027787 Free PMC article.
-
One-Pot Synthesis and Molecular Modeling Studies of New Bioactive Spiro-Oxindoles Based on Uracil Derivatives as SARS-CoV-2 Inhibitors Targeting RNA Polymerase and Spike Glycoprotein.Pharmaceuticals (Basel). 2022 Mar 20;15(3):376. doi: 10.3390/ph15030376. Pharmaceuticals (Basel). 2022. PMID: 35337173 Free PMC article.
-
Novel eco-friendly [1,2,4]triazolo[3,4-a]isoquinoline chalcone derivatives efficiency against fungal deterioration of ancient Egyptian mummy cartonnage, Egypt.Arch Microbiol. 2023 Jan 7;205(2):57. doi: 10.1007/s00203-022-03395-7. Arch Microbiol. 2023. PMID: 36609727 Free PMC article.
-
Antimicrobial and Anti-Inflammatory Activity of Apple Polyphenol Phloretin on Respiratory Pathogens Associated With Chronic Obstructive Pulmonary Disease.Front Cell Infect Microbiol. 2021 Nov 22;11:652944. doi: 10.3389/fcimb.2021.652944. eCollection 2021. Front Cell Infect Microbiol. 2021. PMID: 34881190 Free PMC article.
-
(2E)-2-Benzyl-idene-5,6-dimethoxy-indan-1-one.Acta Crystallogr Sect E Struct Rep Online. 2010 Sep 11;66(Pt 10):o2531-2. doi: 10.1107/S1600536810035695. Acta Crystallogr Sect E Struct Rep Online. 2010. PMID: 21587524 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Chemical Information
