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Case Reports
. 2007 May;56(5):871-3.
doi: 10.1016/j.jaad.2006.10.026. Epub 2006 Nov 17.

Oral histoplasmosis after radiation therapy for laryngeal squamous cell carcinoma

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Case Reports

Oral histoplasmosis after radiation therapy for laryngeal squamous cell carcinoma

Khaled Ezzedine et al. J Am Acad Dermatol. 2007 May.

Abstract

Histoplasmosis is a usually asymptomatic deep fungal infection of tropical origin with respiratory entry and possible oral, pharyngeal, or metastatic localization. The condition represents an important imported systemic mycosis with oral involvement. We report the case of a patient who developed an oropharyngeal reactivation of a latent Histoplasma infection after receiving local antitumoral radiation therapy of the neck. H capsulatum was shown to be present in the lesion by both histopathology and staining, and was deduced to be the causative organism of the disease.

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