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Case Reports
. 2006;59(12):1359-62.
doi: 10.1016/j.bjps.2006.01.024. Epub 2006 May 11.

Multiple malignant melanomas in association with neurofibromatosis type 1

C B Barringer  1 , S J Gorse, H S Rigby, C D Reid
Affiliations
Case Reports

Multiple malignant melanomas in association with neurofibromatosis type 1

C B Barringer et al. J Plast Reconstr Aesthet Surg. 2006.

Abstract

We present a case of multiple primary malignant melanomata occurring over a six year period in a 63-year-old Caucasian man with neurofibromatosis type 1. There is doubt regarding a definite association between these two diseases despite a number of case reports and clear, potential pathological mechanisms. This case not only strengthens support for an association but also highlights the great difficulties that arise in the management of cutaneous melanomata in patients with neurofibromatosis.

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