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Review
. 2007 Feb;189(3):674-82.
doi: 10.1128/JB.01257-06. Epub 2006 Nov 17.

Evolution of catabolic pathways: Genomic insights into microbial s-triazine metabolism

Affiliations
Review

Evolution of catabolic pathways: Genomic insights into microbial s-triazine metabolism

N Shapir et al. J Bacteriol. 2007 Feb.
No abstract available

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Figures

FIG. 1.
FIG. 1.
General structure of s-triazine compounds undergoing microbial metabolism (upper left, inset) and the most broadly demonstrated pathway for catabolism of the herbicide atrazine.
FIG. 2.
FIG. 2.
Metabolism encoded by plasmid genes trzN, atzB, and atzC showing the number of substituent permutations known to be processed by each enzyme. TrzN will displace the eight leaving groups shown and tolerate most combinations of the N-alkyl substituents displaced by AtzB and AtzC, except when R1 = R2 = H or R1 = R2 = CH3.
FIG. 3.
FIG. 3.
Genes, enzymes, and pathways in A. aurescens TC1 proposed to be involved in metabolism of amines liberated from s-triazine compounds by AtzB and AtzC. The gene designations refer to GenBank loci in accession numbers CP000474 (chromosome and plasmid), CP000475 (pTC1), and CP000476 (plasmid pTC2.)
FIG. 4.
FIG. 4.
Features of nitrogen assimilation by Arthrobacter showing plasmid-encoded metabolism (outside the circle) and chromosome-encoded metabolism (inside the circle). The lower half outside the circle represents metabolisms from different Arthrobacter strains, where the metabolism was established to be plasmid encoded (11-15). The upper half outside the circle represents metabolism from A. aurescens TC1, predicted by annotation to be encoded by plasmid genes.

References

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