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Review
. 2006 Dec:21:380-7.
doi: 10.1152/physiol.00019.2006.

Altered cardiac myocyte Ca regulation in heart failure

Donald M Bers  1
Affiliations
Free article
Review

Altered cardiac myocyte Ca regulation in heart failure

Donald M Bers. Physiology (Bethesda). 2006 Dec.
Free article

Abstract

Ca is critical in both the electrical and mechanical properties of cardiac myocytes, and much is known about ionic currents and the normal excitation-contraction coupling process. In heart failure, there are significant alterations in how myocyte Ca is regulated, and these alterations are critical in dictating both contractile dysfunction and certain cardiac arrhythmias that are characteristic of heart failure.

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