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Case Reports
. 2006 Sep-Oct;10(5):251-6.

Solitary plasmacytoma of the spine: a 22 years follow-up case report

M Cappuccio  1 , F De Iure, A Gasbarrini, S Bandiera, S Boriani
Affiliations
  • PMID: 17121318
Case Reports

Solitary plasmacytoma of the spine: a 22 years follow-up case report

M Cappuccio et al. Eur Rev Med Pharmacol Sci. 2006 Sep-Oct.

Abstract

Background and objectives: Plasmacytoma is a systemic malignancy and it is the most frequent primary tumor affecting the skeleton. Progression from solitary plasmacytoma to systemic diffusion is reported to be 65-100% in 15 years. A case report of a rare 22-year follow-up of a thoracic solitary plasmacytoma is here presented.

Material and methods: Clinical case analysis, radiographs, magnetic resonance images and histological sections of the lesion are discussed. Repeated surgical interventions were required due to progression and local recurrence of disease.

Results: Although the inadequate surgical treatment, low response to chemotherapy and radiation therapy, and many local recurrences, no systemic diffusion of the disease was observed in 22 years.

Discussion: Aggressive surgery may be indicated in young patients with isolated lesion and good prognostic factors. Palliative surgery remains necessary in order to decompress the cord and to stabilize the spine.

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