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. 1990 Dec 20;19(13):819-21.
doi: 10.1002/bms.1200191305.

Fast atom bombardment mass spectrometric analysis of arginine-containing neuropeptides

J Silberring  1 , F Nyberg
Affiliations

Fast atom bombardment mass spectrometric analysis of arginine-containing neuropeptides

J Silberring et al. Biomed Environ Mass Spectrom. .

Abstract

A new procedure using fast atom bombardment mass spectrometry for the determination of arginine residues in neuropeptides is described. The technique is based on the modification of the arginine side-group with 1,2-cyclohexanedione. This novel procedure may have a potential use in the study of neuropeptides and their processing and degrading enzymes.

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