Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2006 Nov 24;314(5803):1243; author reply 1243.
doi: 10.1126/science.1129918.

Comment on papers by Chong et al., Nishio et al., and Suri et al. on diabetes reversal in NOD mice

Denise L Faustman  1 , Simon D Tran, Shohta Kodama, Beatrijs M Lodde, Ildiko Szalayova, Sharon Key, Zsuzsanna E Toth, Eva Mezey
Affiliations
Comment

Comment on papers by Chong et al., Nishio et al., and Suri et al. on diabetes reversal in NOD mice

Denise L Faustman et al. Science. .

Abstract

Chong et al., Nishio et al., and Suri et al. (Reports, 24 March 2006, pp. 1774, 1775, and 1778) confirmed that treating nonobese diabetic (NOD) mice with an immune adjuvant and semisyngenic spleen cells can reverse the disease but found that spleen cells did not contribute to the observed recovery of pancreatic islets. We show that islet regeneration predominately originates from endogenous cells but that introduced spleen cells can also contribute to islet recovery.

PubMed Disclaimer

Comment on

Publication types

MeSH terms

LinkOut - more resources