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. 2007 Feb 15;17(4):1091-7.
doi: 10.1016/j.bmcl.2006.11.016. Epub 2006 Nov 10.

1,3-Disubstituted-imidazo[1,5-a]pyrazines as insulin-like growth-factor-I receptor (IGF-IR) inhibitors

Mark J Mulvihill  1 , Qun-Sheng Ji, Doug Werner, Patricia Beck, Cara Cesario, Andrew Cooke, Matthew Cox, Andrew Crew, Hanqing Dong, Lixin Feng, K W Foreman, Gilda Mak, Anthony Nigro, Matthew O'Connor, Lydia Saroglou, Kathryn M Stolz, Izabela Sujka, Brian Volk, Qinghua Weng, Robin Wilkes
Affiliations

1,3-Disubstituted-imidazo[1,5-a]pyrazines as insulin-like growth-factor-I receptor (IGF-IR) inhibitors

Mark J Mulvihill et al. Bioorg Med Chem Lett. .

Abstract

A series of novel 8-amino-1,3-disubstituted-imidazo[1,5-a]pyrazines was designed and synthesized as IGF-IR inhibitors.

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