Another job for the talented p120-catenin
- PMID: 17129772
- DOI: 10.1016/j.cell.2006.11.014
Another job for the talented p120-catenin
Abstract
Given the complexity of signaling pathways in the cell, it is a mystery how these pathways communicate with one other. In this issue of Cell, Wildenberg et al. (2006) reveal that the key effector molecule p120-catenin can mediate crosstalk between the Rac and Rho signaling pathways.
Comment on
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p120-catenin and p190RhoGAP regulate cell-cell adhesion by coordinating antagonism between Rac and Rho.Cell. 2006 Dec 1;127(5):1027-39. doi: 10.1016/j.cell.2006.09.046. Cell. 2006. PMID: 17129786
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