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. 2006 Nov 28;67(10):1852-4.
doi: 10.1212/01.wnl.0000244490.07925.8b.

Reduction of optic nerve fibers in patients with Alzheimer disease identified by laser imaging

H V Danesh-Meyer  1 , H Birch, J Y-F Ku, S Carroll, G Gamble
Affiliations

Reduction of optic nerve fibers in patients with Alzheimer disease identified by laser imaging

H V Danesh-Meyer et al. Neurology. .

Abstract

In this case-control study, we compared the optic nerves (ONs) by clinical examination and scanning laser ophthalmoscopy (SLO) of 40 patients with Alzheimer disease (AD) and 50 controls. There was a reduction in the number of ON fibers in patients with AD, with a threefold greater odds ratio for a larger optic cup-to-disc ratio in patients with AD.

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