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Clinical Trial
. 2006 Nov 28;67(10):1872-5.
doi: 10.1212/01.wnl.0000244421.73986.09.

Efficacy of carbamazepine and valproate as monotherapy for early epilepsy and single seizures

A G Marson  1 , P R Williamson, S Taylor, M Maguire, D W Chadwick
Affiliations
Clinical Trial

Efficacy of carbamazepine and valproate as monotherapy for early epilepsy and single seizures

A G Marson et al. Neurology. .

Abstract

In the Multi-Centre Study of Early Epilepsy and Single Seizures (MESS), patients were randomly allocated to immediate or delayed antiepileptic drug treatment. For time to first seizure recurrence, MESS provides strong evidence of an effect for carbamazepine as monotherapy but mixed evidence of an effect for valproate.

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