Binding activity of norovirus and sapovirus to histo-blood group antigens
- PMID: 17131063
- DOI: 10.1007/s00705-006-0883-z
Binding activity of norovirus and sapovirus to histo-blood group antigens
Abstract
Noroviruses (NoVs) and sapoviruses (SaVs) are causative agents of human gastroenteritis. There is increasing evidence that certain human NoV strains bind to histo-blood group antigens (HBGAs). We found that several NoV virus-like particles (VLPs) showed binding activity to HBGAs, while neither SaV genogroup I (GI) VLP nor SaV GV VLP showed such activity.
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