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. 1991 Aug;59(8):2843-5.
doi: 10.1128/iai.59.8.2843-2845.1991.

In vitro neutralization of Chlamydia trachomatis by monovalent Fab antibody specific to the major outer membrane protein

Affiliations

In vitro neutralization of Chlamydia trachomatis by monovalent Fab antibody specific to the major outer membrane protein

H Su et al. Infect Immun. 1991 Aug.

Abstract

Monovalent Fab antibodies to serovar- and subspecies-specific epitopes of the major outer membrane protein (MOMP) of Chlamydia trachomatis neutralized infectivity for hamster kidney cells by preventing chlamydial attachment. These findings exclude the aggregation of chlamydiae as a mechanism of anti-MOMP neutralization and provide additional evidence in support of the MOMP as a chlamydial adhesin.

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