Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2007 Feb;45(2):662-5.
doi: 10.1128/JCM.02058-06. Epub 2006 Nov 29.

Burkholderia glumae infection in an infant with chronic granulomatous disease

Jason B Weinberg  1 , Barbara D Alexander, Joseph M Majure, Larry W Williams, Jason Y Kim, Peter Vandamme, John J LiPuma
Affiliations
Case Reports

Burkholderia glumae infection in an infant with chronic granulomatous disease

Jason B Weinberg et al. J Clin Microbiol. 2007 Feb.

Abstract

An 8-month-old boy developed a necrotic lung mass from which Burkholderia glumae was recovered, leading to the diagnosis of chronic granulomatous disease (CGD). While other Burkholderia species have been identified as important pathogens in persons with CGD, B. glumae has not been previously reported to cause human infection.

PubMed Disclaimer

Figures

FIG. 1.
FIG. 1.
CT of the chest demonstrating a 3.9- by 4.4-cm mass within the lower lobe of the left lung (arrow) and numerous smaller nodules in both lungs.
FIG. 2.
FIG. 2.
Dendrogram derived from the unweighted-pair group average linkage of correlation coefficients between the protein patterns of strain AU6208 and reference strains of B. glumae, B. gladioli, and B. plantarii. The rule at the top shows the percent similarity.
See this image and copyright information in PMC

References

    1. Ahlin, A., M. De Boer, D. Roos, J. Leusen, C. I. Smith, U. Sundin, H. Rabbani, J. Palmblad, and G. Elinder. 1995. Prevalence, genetics and clinical presentation of chronic granulomatous disease in Sweden. Acta Paediatr. 84:1386-1394. - PubMed
    1. Bottone, E. J., S. D. Douglas, A. R. Rausen, and G. T. Keusch. 1975. Association of Pseudomonas cepacia with chronic granulomatous disease. J. Clin. Microbiol. 1:425-428. - PMC - PubMed
    1. Boyanton, B. L., Jr., L. M. Noroski, H. Reddy, M. K. Dishop, M. J. Hicks, J. Versalovic, and E. H. Moylett. 2005. Burkholderia gladioli osteomyelitis in association with chronic granulomatous disease: case report and review. Pediatr. Infect. Dis. J. 24:837-839. - PubMed
    1. Brisse, S., S. Stefani, J. Verhoef, A. Van Belkum, P. Vandamme, and W. Goessens. 2002. Comparative evaluation of the BD Phoenix and VITEK 2 automated instruments for identification of isolates of the Burkholderia cepacia complex. J. Clin. Microbiol. 40:1743-1748. - PMC - PubMed
    1. Bylund, J., P. A. Campsall, R. C. Ma, B. A. Conway, and D. P. Speert. 2005. Burkholderia cenocepacia induces neutrophil necrosis in chronic granulomatous disease. J. Immunol. 174:3562-3569. - PubMed

Publication types

MeSH terms

Associated data

LinkOut - more resources