Time trends in socioeconomic differences in incidence rates of cancers of gastro-intestinal tract in Finland

Abstract

Background: The magnitude of socioeconomic differences in health varies between societies, and over time within a given society. We studied the association between social class and incidence of cancers of the gastro-intestinal tract over time in a large cohort in Finland.

Methods: We studied social class variation among 45-69 year-old Finns during 1971-95 in incidence of cancers of the gastro-intestinal tract by means of a computerized record linkage of the Finnish Cancer Registry and the 1970 Population Census, which included social class data.

Results: There were 2.3 million individuals in the cohort under follow-up, with 1622 cases of cancer of the esophagus, 8069 stomach (non-cardia), 1116 cardia, 408 small intestine, 6361 colon, 5274 rectum, 1616 liver, 1756 gallbladder, and 5084 pancreas during 1971-1995. Cancers of the esophagus, stomach, cardia, gallbladder and pancreas were most common among persons belonging to a low social class. Cancers of the small intestine in males only, colon in both genders, and rectum in females were most common in the higher social classes. Incidence of stomach cancer decreased and incidence of colon cancer increased over time in both genders in all social classes, and the large differences between social classes remained unchanged over time. Incidence rates of cardia cancer did not change substantially over time.

Conclusion: There is a large variation in incidence of cancer of the gastrointestinal tract by social class in Finland. Although much of the observed social class differences probably could be explained by known etiological factors such as diet, physical exercise, alcohol consumption, smoking and exogenous hormone use, part of the variation is apparently attributable to largely unknown factors.

Figure 1

Age adjusted incidence of Esophageal cancers histological types among Finns aged 45–64 at the beginning of each 5-years period between 1971–1995.

Figure 2

Age adjusted incidence of Stomach non-cardia and Cardia cancers among Finns aged 45–64 at the beginning of each 5-years period between 1971–1995.

Figure 3

Age adjusted incidence of Colon and Rectum cancers among Finns aged 45–64 at the beginning of each 5-years period between 1971–1995.

Figure 4

Age adjusted incidence of Liver and Gall bladder and biliary tract cancers among Finns aged 45–64 at the beginning of each 5-years period between 1971–1995.

Figure 5

Age adjusted incidence of Small intestine and Pancreas cancers among Finns aged 45–64 at the beginning of each 5-years period between 1971–1995.