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. 2007 Mar 1;44(3):306-8.
doi: 10.1097/QAI.0b013e31802c83d9.

Gender differences in AIDS-associated Kaposi sarcoma in Harare, Zimbabwe

Amie L Meditz  1 , Margaret Borok, Samantha MaWhinney, Ivy Gudza, Buxton Ndemera, Lovemore Gwanzura, Thomas B Campbell
Affiliations

Gender differences in AIDS-associated Kaposi sarcoma in Harare, Zimbabwe

Amie L Meditz et al. J Acquir Immune Defic Syndr. .

Abstract

Reasons for gender-related differences in the risk of AIDS-related Kaposi sarcoma (AIDS-KS) are unknown. Four hundred thirty-eight male and 166 female AIDS-KS patients were evaluated in Harare, Zimbabwe. Female patients were younger than male patients in this study (median of 33 vs. 38 years; P < 0.001), mirroring the epidemiology of AIDS in Zimbabwe. In a multivariate model adjusted for CD4 T-cell count, age, prior radiation treatment, and chemotherapy, women were more likely to report fever, diaphoresis, or weight loss (odds ratio = 1.7, 95% confidence interval: 1.1 to 2.7; P = 0.009). These findings suggest an increased severity of KS or other unidentified infections among women with AIDS-KS in Zimbabwe.

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