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. 2004:(48):65-6.
doi: 10.1093/nass/48.1.65.

Synthesis and base recognition ability of oligoribonucleotides incorporating 2'-O-methyl-3-deazaguanosine

Kohji Seio  1 , Takeshi Sasami, Mitsuo Sekine
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Synthesis and base recognition ability of oligoribonucleotides incorporating 2'-O-methyl-3-deazaguanosine

Kohji Seio et al. Nucleic Acids Symp Ser (Oxf). 2004.

Abstract

2'-O-methyl-oligoribonucleotides incorporating a 3-deazaguanine (3DG) were synthesized. Melting temperature (Tm value) analysis indicates the stability and base discriminating ability of the 2'-O-methyl-RNA/RNA duplex.

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