doi: 10.1093/nass/48.1.207.
Synthesis and alternate-stranded triplex forming ability of novel alpha-beta chimeric oligonucleotides bearing an intercalator-conjugated nucleobase
Affiliations
- PMID: 17150551
- DOI: 10.1093/nass/48.1.207
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Synthesis and alternate-stranded triplex forming ability of novel alpha-beta chimeric oligonucleotides bearing an intercalator-conjugated nucleobase
Nucleic Acids Symp Ser (Oxf).
2004.
Abstract
A series of novel alpha-beta chimeric oligonucleotides bearing anthraquinone-attached nucleobase at linker position, were synthesized as a triplex-forming oligonucleotide (TFO). Their ability to stabilize the alternate-stranded triple helix was investigated through the UV-melting experiments.
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