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Review
. 2007 Feb;12(1):54-63.
doi: 10.1016/j.siny.2006.10.007. Epub 2006 Dec 6.

Iron in fetal and neonatal nutrition

Raghavendra Rao  1 , Michael K Georgieff
Affiliations
Review

Iron in fetal and neonatal nutrition

Raghavendra Rao et al. Semin Fetal Neonatal Med. 2007 Feb.

Abstract

Both iron deficiency and iron excess during the fetal and neonatal period bode poorly for developing organ systems. Maternal conditions such as iron deficiency, diabetes mellitus, hypertension and smoking, and preterm birth are the common causes of perinatal iron deficiency. Long-term neurodevelopmental impairments and predisposition to future iron deficiency that are prevalent in infants with perinatal iron deficiency require early diagnosis, optimal treatment and adequate follow-up of infants at risk for the condition. However, due to the potential for oxidant-mediated tissue injury, iron overload should be avoided in the perinatal period, especially in preterm infants.

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References

    1. Panel on Micronutrients Subcommittee on Upper Reference Levels of Nutrients and of Interpretation and Uses of Dietary Reference Intakes, and the Standing Committee on the Scientific Evaluation of Dietary Reference Intakes Food and Nutrition Board, Institute of Medicine . Dietary reference intakes for vitamin a, vitamin k, arsenic, boron, chromium, copper, iodine, iron, manganese, molybdenum, nickel, silicon, vanadium and zinc. National Academy Press; Washington, DC: 2001. Iron; pp. 290–393.
    1. Siimes AS, Siimes MA. Changes in the concentration of ferritin in the serum during fetal life in singletons and twins. Early Hum Dev. 1986;13:47–52. - PubMed
    1. Scholl TO. Iron status during pregnancy: setting the stage for mother and infant. Am J Clin Nutr. 2005;81:1218S–22. - PubMed
    1. Steer PJ. Maternal hemoglobin concentration and birth weight. Am J Clin Nutr. 2000;71:1285S–7. - PubMed
    1. Kilbride J, Baker TG, Parapia L, Khoury SA, Shugaidef SW, Jerwood D. Anaemia during pregnancy as a risk factor for iron-deficiency anaemia in infancy: a case-control study in Jordan. Int J Epidemiol. 1999;28:461–8. - PubMed