Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2006 Dec;142(6):1068-70.
doi: 10.1016/j.ajo.2006.06.048.

Retinal pigment epithelium tear after intravitreal bevacizumab for exudative age-related macular degeneration

Ulrich H M Spandau  1 , Jost B Jonas
Affiliations

Retinal pigment epithelium tear after intravitreal bevacizumab for exudative age-related macular degeneration

Ulrich H M Spandau et al. Am J Ophthalmol. 2006 Dec.

Abstract

Purpose: To report on the development of retinal pigment epithelium tears after intravitreal injections of bevacizumab as treatment of exudative age-related macular degeneration (AMD).

Design: Interventional case series.

Methods: The study included 63 patients who received an intravitreal injection of 1.5 mg bevacizumab as treatment of a detachment of the retinal pigment epithelium attributable to AMD and who had a follow-up of at least two months.

Results: Four patients (6%) developed a tear of the retinal pigment epithelium in the parafoveal region. Compared with the baseline value, visual acuity at the end of follow-up remained stable in three patients and declined in the fourth patient.

Conclusions: Intravitreal injections of bevacizumab may be followed by a tear of the retinal pigment epithelium in eyes with exudative AMD and a retinal pigment epithelium detachment.

PubMed Disclaimer

MeSH terms

LinkOut - more resources