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Comparative Study
. 2006 Dec 12;67(11):2070-2.
doi: 10.1212/01.wnl.0000247667.89251.43.

A rapid screening battery to identify frontal dysfunction in patients with ALS

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Comparative Study

A rapid screening battery to identify frontal dysfunction in patients with ALS

Claire Flaherty-Craig et al. Neurology. .

Abstract

We studied the relationship between verbal associative fluency, verbal abstract reasoning, and judgment in ALS using a 20-minute screening evaluation. Deficiencies in these measures were found in 20.0%, 18.6%, and 35.7% of patients with limb-onset ALS and in 37.5%, 25.0%, and 60.0% of patients with bulbar-onset ALS. This simple screen identifies deficits that affect discussions of treatment interventions and end-of-life issues.

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