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Randomized Controlled Trial
. 2005 Jun;21(2):84-7, 91.

[The comparison study of glaucoma trabeculectomy applying amniotic membrane or mitomycin C]

[Article in Chinese]
Kangkeng Zheng  1 , Zicai Huang, Haitang Zou, Hongni Li, Yixia Huang, Mingliang Xie
Affiliations
  • PMID: 17165335
Randomized Controlled Trial

[The comparison study of glaucoma trabeculectomy applying amniotic membrane or mitomycin C]

[Article in Chinese]
Kangkeng Zheng et al. Yan Ke Xue Bao. 2005 Jun.

Abstract

Purpose: To probe the results of trabeculectomy with human amniotic membrane (HAM) or mitomycin(MMC) in the treatment of glaucoma.

Methods: In a randomized control clinical trial, 48 eyes of 28 glaucoma patients were divided into two groups, each group has 24 eyes, and each group was divided into two sub-groups according to the age. The former was underwent trabeculectomy with HAM transplanted, the later was administrated intra operatively with MMC, 0.2-0.4mg/ml, for 2-4 minutes, the follow-up was 6 months.

Results: The operation success rate of both groups was higher than the standard trabeculectomy, and the difference between the two groups was not significant. Complications induced by HAM were mainly shallow anterior chamber, whereas by MMC were thin wall bleb, bleb leaking, persistent hypotony and hypotonous maculopathy.

Conclusion: Application properly HAM or MMC can improved the operation success rate, maintain the functional bleb long time and decreased the complications.

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