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Review
. 2006 Nov 21;1(10):615-8.
doi: 10.1021/cb600439h.

Regulation and specificity of S-nitrosylation and denitrosylation

Steven R Tannenbaum  1 , Forest M White
Affiliations
Review

Regulation and specificity of S-nitrosylation and denitrosylation

Steven R Tannenbaum et al. ACS Chem Biol. .

Abstract

Signal transduction from nitric oxide (NO) is important in physiological processes such as smooth muscle relaxation and neurotransmission. NO signaling occurs through a variety of mechanisms, including S-nitrosylation (SNO) of sulfhydryl groups in protein. A paper in this issue of the journal dissects the regulatory system involved in SNO of caspase-3 and highlights the need for more direct investigations of the complex biological regulation by NO signaling.

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