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Review
. 1991 Aug;12(8):277-82.
doi: 10.1016/0167-5699(91)90126-E.

T-cell recognition of myelin basic protein

K W Wucherpfennig  1 , H L Weiner, D A Hafler
Affiliations
Review

T-cell recognition of myelin basic protein

K W Wucherpfennig et al. Immunol Today. 1991 Aug.

Abstract

Multiple sclerosis is a chronic inflammatory disease of the central nervous system which has been hypothesized to be autoimmune in nature. To test whether this is the case, Kai Wucherpfennig and colleagues have developed a set of criteria that must be met to satisfy the hypothesis. Here, they present these criteria and assess the extent to which studies to date satisfy them.

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Comment in

  • Viral homologies with myelin basic protein.
    Souberbielle BE, Kemp G, Russell WC. Souberbielle BE, et al. Immunol Today. 1991 Dec;12(12):464-5. doi: 10.1016/0167-5699(91)90022-L. Immunol Today. 1991. PMID: 1723879 No abstract available.

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