Clinical trials of endothelin antagonists in heart failure: publication is good for the public health
- PMID: 17170334
- PMCID: PMC1861328
- DOI: 10.1136/hrt.2006.089250
Clinical trials of endothelin antagonists in heart failure: publication is good for the public health
Abstract
The failure of endothelin antagonists to show benefit in heart failure cannot be understood until all the clinical trials are fully published.
Conflict of interest statement
Competing interests: NFK is a British Heart Foundation Junior Research Fellow (FS/03/006/15108) and has received grants to attend conferences from Merck, Pfizer and Sanofi. DJW has, in the past, advised Abbott, Actelion, Roche and Bristol‐Myers Squibb on the development of ET antagonists, and has undertaken clinical studies using ET antagonists with Astra‐Zeneca, Bristol‐Myers Squibb, Encysive, Takeda and Vanguard. NFK and DJW have received donations of ET antagonists from Abbott Pharmaceuticals for use in their preclinical research.
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