Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2007 Jan;8(1):58-69.
doi: 10.1038/nrg2025.

The mouse as a model for human biology: a resource guide for complex trait analysis

Luanne L Peters  1 , Raymond F Robledo, Carol J Bult, Gary A Churchill, Beverly J Paigen, Karen L Svenson
Affiliations
Review

The mouse as a model for human biology: a resource guide for complex trait analysis

Luanne L Peters et al. Nat Rev Genet. 2007 Jan.

Abstract

The mouse has been a powerful force in elucidating the genetic basis of human physiology and pathophysiology. From its beginnings as the model organism for cancer research and transplantation biology to the present, when dissection of the genetic basis of complex disease is at the forefront of genomics research, an enormous and remarkable mouse resource infrastructure has accumulated. This review summarizes those resources and provides practical guidelines for their use, particularly in the analysis of quantitative traits.

PubMed Disclaimer

LinkOut - more resources