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Comment
. 2006 Dec 15;127(6):1097-9.
doi: 10.1016/j.cell.2006.11.030.

Sensory neurons link the nervous system and autoimmune diabetes

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Sensory neurons link the nervous system and autoimmune diabetes

Helene Bour-Jordan et al. Cell. .
Free article

Abstract

The initial factors that trigger the autoimmune response against pancreatic islets in the nonobese diabetic (NOD) mouse are still unknown. In this issue of Cell, propose that a defect in a subset of sensory neurons innervating the pancreas plays a major role in initiating the chain of events that will lead to local inflammation, islet destruction, and autoimmune diabetes.

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