Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2006 Dec;25(6):857-9.
doi: 10.1016/j.immuni.2006.11.007.

The ins and outs of MHC class II proteins in dendritic cells

Laura Santambrogio  1 , Jack L Strominger
Affiliations
Free article
Review

The ins and outs of MHC class II proteins in dendritic cells

Laura Santambrogio et al. Immunity. 2006 Dec.
Free article

Abstract

One more mechanism for regulating surface expression of MHC class II proteins in dendritic cells (an important process that regulates both tolerance and immunity) has been uncovered, polyubiquitination of Lys225 in the intracytoplasmic region and subsequent endocytosis and proteolysis (Omura-Hoshino et al., 2006; van Neil et al., 2006; Shin et al., 2006).

PubMed Disclaimer

Comment on

MeSH terms

Substances

LinkOut - more resources