Review
doi: 10.1016/j.immuni.2006.11.005.
Maintaining hematopoietic stem cells in the vascular niche
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- PMID: 17174928
- DOI: 10.1016/j.immuni.2006.11.005
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Review
Maintaining hematopoietic stem cells in the vascular niche
Immunity.
2006 Dec.
Free article
Abstract
In this issue of Immunity, Sugiyama et al. (2006) provide evidence that most bone-marrow hematopoietic stem cells (HSCs) reside in vascular niches containing reticular cells that secrete CXCL12, a chemokine that promotes HSC maintenance.
Comment on
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Maintenance of the hematopoietic stem cell pool by CXCL12-CXCR4 chemokine signaling in bone marrow stromal cell niches.Immunity. 2006 Dec;25(6):977-88. doi: 10.1016/j.immuni.2006.10.016. Immunity. 2006. PMID: 17174120
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